Endocrine Abstracts

Aim: To assess the utility of early detection of diabetic peripheral neuropathy using Vibration perception threshold (VPT) via digital Biothesiometer and correlation with patient reported symptoms. Type of study: Audit of peripheral neuropathy assessment in all diabetes patients Standard: NICE guideline on Diabetic foot problems (NG 19- Updated October 2019)Methods: The NICE guidelines recommend neuropathy assessment on all patients with Type 2 Diabetes....

Thyroid storm is a rarely seen complication of Thyrotoxicosis complicated by multiple organ dysfunctions. Early recognition is crucial in reducing morbidity and mortality. We present the case of a young lady admitted with traumatic fracture of Tibia and Fibula. She was noted to be in rapid AF and on examination manifested signs of Thyrotoxicosis with palpable goitre. She was noted to be hyperthermic and emotionally labile and confused with signs of right heart failure.Investig...

VHL is an autosomal dominant familial cancer syndrome with renal, CNS and pancreato-biliary manifestations in addition to phaeochromocytoma (PC)/paraganglioma (PGL). Importantly, there is a partial genotype–phenotype correlation, with kindreds harboring deletions and mutations of the VHL gene leading to premature termination/truncation not manifesting PC/PGL. As genetic testing in PC/PGL moves from a research-focus into clinical service, knowledge and understanding...

Introduction: The hypothalamus plays a pivotal role in maintaining body temperature.Insults to the hypothalamus can result in life threatening temperature disturbance.We describe a case of hypothalamic dysfunction presenting with poikilothermia that was managed with a special portable external heating vest.Case report: A 31 year old man presented in July 1992 with a subarachnoid hemorrhage which was managed s...

Thyroid eye disease is the most frequent extrathyroidal manifestation of Graves’ disease. Severe and active disease is frequently treated with immunosuppressive therapy. IV methylprednisolone (500 mg daily for 3 days) is the treatment of choice with efficacy rates of up to 77%. New onset glucose intolerance/diabetes is the most relevant side effect of this treatment. We investigated the risk of steroid induced diabetes and the risk factors for its development.<p class...